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Research

Research

The Temple Digestive Disease Center has been nationally recognized for its clinical research activities, primarily in gastrointestinal motility disorders. We have also expanded to include Barrett’s esophagus and novel endoscopic approaches to evaluate and treat gastrointestinal disorders.

Our clinical research is supported by NIH grants as well as pharmaceutical and foundation sources. The following lists some of the research interests of our gastroenterologists.

Frank Friedenberg, MD

  • The efficacy of botulinum toxin for the treatment of gastroparesis in a randomized, double-blind, prospective trial
  • Risk factors for the failure of metronidazole in the initial management of C. difficile-associated disease
  • The efficacy of the proton pump inhibitor rabeprazole in improving pulmonary function and symptoms in patients with asthma.

Benjamin Krevsky, MD, MPH

  • Use of laser therapy to treat Barrett's Esophagus and esophageal cancer
  • Scintigraphic techniques in studying GI motility
  • Colon cancer surveillance in heart transplant candidates

Henry Parkman, MD

  • Use of multichannel electrogastrography to assess gastric myoelectrical activity to detect gastric motor function in patients with dyspeptic symptoms
  • Development of a noninvasive test to measure simultaneously both gastric emptying and gastric volume after ingestion of a solid meal under physiologic conditions. This will be useful to define the pathophysiologic factors which cause symptoms in patients with functional dyspepsia and be useful to test the effects of new pharmaceutical agents.

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